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Image Guided Therapy

PROVIDING HIGH RESOLUTION, THREE-DIMENSIONAL IMAGES OF THE OPERATING FIELD IN REAL TIME FOR MINIMALLY INVASIVE PROCEDURES

Imaging techniques like X-ray and MRI are invaluable for treating a wide variety of illnesses and injuries. The challenge remains to shorten the lapse of time between image acquisition and procedure. Patient preference for minimally invasive surgery makes real-time imaging information vital.

Image Guided Therapy (IGT) techniques help improve therapeutic outcomes. By providing precise ways to "visualize" intra-procedural anatomical changes in real time, IGT helps clarify a surgeon's understanding of the patients' anatomy and enables minimally invasive procedures to be performed inside solid organs. Guided by real-time imaging, surgeons can make decisions based on accurate data-sometimes the crucial difference between life and death.

CIMIT's Image Guided Therapy Program is focused on providing precise high-resolution, three-dimensional ways to "visualize" intra-procedural changes in real time, allowing minimally invasive surgery to be performed on solid organs that would otherwise require traditional surgical procedures.

  • Projects
  • Publications
  • Forum/Events
  • In The News
Current Image Guided Therapy Projects
PRINCIPAL INVESTIGATOR INSTITUTION PROJECT TITLE
Yolonda Colson Brigham and Women’s Hospital Validation of Imaging System for Near-Infrared Image Guided Sentinel Lymph Node Dissection in Lung Cancer
Gerald Denis Boston University Ultrasound-directed delivery of cancer chemotherapeutic drugs
Elazar Edelman Massachusetts Institute of Technology High Throughput Flow System for the Generation of Thrombotic Fingerprints
James Ellsmere Beth Israel Deaconess Medical Center An Office-Based System for Accessing Implanted Ports for Laparoscopic Adjustable Gastric Banding
James Ellsmere Beth Israel Deaconess Medical Center Improving Image Guided Pancreatic Procedures Using MR Endoscopy
Fiona Fennessy Brigham and Women’s Hospital Computer-assisted tumor blood vessel tortuosity analysis at 3T, as a method of assessing ablative therapy response
Felipe Fregni Beth Israel Deaconess Medical Center The effect of transcranial direct current stimulation combined with arm training using glove-ArMEO robotic device on motor recovery in traumatic brain injury survivors
Mark Grinstaff Boston University Preparation and Evaluation of Functional Nanospheres
Rajiv Gupta Massachusetts General Hospital Dynamic Imaging and Neuro Interventions Using a High-Resolution Flat-Panel Volume CT: Feasibility  Demonstration
John Guttag          
           
Massachusetts Institute of Technology  
Nobuhiko Hata Brigham and Women’s Hospital Swimming Capsule Endoscope for Diagnosis and Treatment of Small Intestine
Nathan McDannold Brigham and Women’s Hospital Herceptin Delivery to Breast Cancer Metastases in the Central Nervous System Via Focused Ultrasound-Induced Blood-Brain Barrier Disruption
Nobuhiko Nakajima Brigham and Women’s Hospital Real-Time Electromagnetic Navigation for Flexible-Neuroendoscopy
     
     
     
Recent Publications by CIMIT Investigators
INVESTIGATOR/AUTHOR PUBLICATION ARTICLE DATE
Stylopoulos N, Vosburgh KG Surg Innov. 14(2):113-21 Assessing technical skill in surgery and endoscopy: a set of metrics and an algorithm (C-PASS) to assess skills in surgical and endoscopic procedures. 2007
Vosburgh KG, Stylopoulos N, Estepar RS, Ellis RE, Samset E, Thompson CC Gastrointest Endosc. 2007 May; 5(6):866-70 EUS with CT improves efficiency and structure identification over conventional EUS 2007
Dimaio, S., Kapur, T., Cleary, K., Aylward, S., Kazanzides, P., Vosburgh, K., Ellis, R., Duncan, J., Farahani, K., Lemke, H., Peters, T., Lorensen, W. B., Gobbi, D., Haller, J., Clarke, L. L., Pizer, S., Taylor, R., Galloway, Jr., R., Fichtinger, G., Hata, N., Lawson, K., Tempany, C., Kikinis, R., Jolesz, F. Neuroimage 37 Suppl 1:S144-51 Challenges in Image Guided Therapy System Design 2007
Estepar, R. S., Stylopoulos, N., Ellis, R., Samset, E., Westin, C. F., Thompson, C., Vosburgh, K. Comput Aided Surg 12 (6):311-24 An Endoscopic Ultrasound Navigation System for Transgastric Access Procedures 2007
Hoshino, K., Ly, H. Q., Frangioni, J. V., Hajjar, R. J. Prog Cardiovasc Dis 49(6):414-20 In Vivo Tracking in Cardiac Stem Cell Based Therapy 2007
Krissian, K., Westin, C. F., Kikinis, R., Vosburgh, K. G. IEEE Trans Image Process 16(5):1412-20 Oriented Speckle Reducing Anisotropic Diffusion 2007
Parungo, C. P., Soybel, D. I., Colson, Y. L., Kim, S. W., Ohnishi, S., DeGrand, A. M., Laurence, R. G., Soltesz, E. G., Chen, F. Y., Cohn, L. H., Bawendi, M. G., Frangioni, J. V. Ann Surg Oncol 14(2):286-98 Lymphatic Drainage of the Peritoneal Space: A Pattern Dependent on Bowel Lymphatics 2007
       
Image Guided Therapy at the
CIMIT Forum and Past Events
EVENT DATE SPEAKERS DETAIL
Forum: Stroke Prevention and Therapy Apr. 15, 2008

Michael H. Lev, MD: MGH

Javier Romero, MD: MGH

Patient Selection for Novel Stroke Therapy Using
Advance Imaging

New Perspectives in the Imaging of Carotid Artery Plaque

Forum: Virtual Meets Reality in Image Guided Intervention Apr. 8, 2008

David Hawkes, PhD, FREng, FInstP, FIPEM: University College London and co-Founder, IXICO Ltd.

Polina Golland, PhD: MIT

• Integrating Models and Imaging to Guide Interventions

• Functional Hierarchy: Representation and Modeling of Spatial Patterns of Activation in fMRI

Forum: Imaging
Leads to
Improvement of
Medical Care
Oct. 2,
2007
Gordon Harris, PhD; MGH, HMS

Leonard Kaban, DMD, MD; MGH, Harvard School of Dental Medicine
•3D Imaging in Radiology

•Bone Lengthening by
Distraction Osteogenesis
(DO)
Forum: Developments in Computer Tomography (CT) Jan. 16, 2007 George Chen, PhD; MGH

Rajiv Gupta, MD, PhD; MGH, HMS      
• Functional CT: Visualization of Dynamic Processes Using Computed Tomography

• Image Guided Radiotherapy of Moving Targets
Image Guided Therapy News
ARTICLE TITLE PUBLICATION DATE
Endoscopes Push Imaging Boundaries: Dating Back Centuries, Endoscopy Takes Advantage of Today’s Cutting Edge Technologies Advanced Imaging Magazine July 8, 2008
He develops robotics to assist surgery Boston Globe May 7, 2007
Tiny Souped-Up Scope

 

Technology Review Oct. 20, 2006
     
Video
 

Ferenc Jolesz, MDProgram Leaders

Ferenc Jolesz, MD
jolesz@bwh.harvard.edu


CIMIT RESPONSIBILITIES
Co-Program Leader,
Image Guided Therapy

Ron Kikinis, MD

Ron Kikinis, MD
kikinis
@bwh.harvard.edu


CIMIT RESPONSIBILITIES
Co-Program Leader,
Image Guided Therapy

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Related Links

National Center for Image-Guided Therapy Website

AMIGO: Advanced Multimodality Image Guided Operating Room
Brigham and Women’s Hospital

 

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