CIMIT Program: Trauma & Casualty Care

Trauma & Casualty Care

PREVENTING DEATHS IN THE CRITICAL MINUTES FOLLOWING TRAUMA

Trauma care has improved dramatically. A victim with near-fatal injuries who reaches the hospital alive is likely to survive. However, little progress has been made to treat patients in the critical period before they reach a treatment facility. As a result, most traumatic deaths occur in the pre-hospital setting and before any meaningful medical intervention becomes available. Translational research efforts are targeting the early phases of an injury in order to develop novel therapies and interventions for prehospital and early in-hospital trauma care.

CIMIT’s Trauma & Casualty Care Program works to facilitate projects that enable first responders to stabilize patients at the site of the casualty, offering critical care to the patient rapidly and effectively. Several projects aim to explore solutions to stop internal and external bleeding as well as improve resuscitation and survival.

Solutions
Publications
Forum/Events
In The News
Multimedia

CIMIT-Supported
Trauma & Casualty Care Solutions

Develop new tools for first-responders that can quickly detect and reduce internal bleeding

Develop a method of rapidly lowering the body's temperature in the first moments of injury to help keep patients alive

Connect the pre-hospital ambulance and in-hospital trauma teams by telemedicine

Explore fluidless resuscitation as a method to decrease mortality and organ failures

» View all CIMIT-Funded Projects.

Contact Haleh Armian, CIMIT Senior Manager, Business Development
for more information regarding Commercialization Opportunities.

Recent Publications by CIMIT Investigators
INVESTIGATOR/AUTHOR	PUBLICATION	ARTICLE	DATE
Alam, H. B., Shults, C., Ahuja, N., Ayuste, E. C., Chen, H., Koustova, E., Sailhamer, E. A., Li, Y., Liu, B., de Moya, M., Velmahos, G. C.	Resuscitation Sep 4, 2007	Impact of Resuscitation Strategies on the Acetylation Status of Cardiac Histones in a Swine Model of Hemorrhage	2007
Sailhamer, E. A., Chen, Z., Ahuja, N., Velmahos, G. C., de Moya, M., Rhee, P., Shults, C., Alam, H. B.	J Am Coll Surg 204(4):642-53	Profound Hypothermic Cardiopulmonary Bypass Facilitates Survival without a High Complication Rate in a Swine Model of Complex Vascular, Splenic, and Colon Injuries	2007
Velmahos, G. C., Spaniolas, K., Duggan, M., Alam, H. B., Tabbara, M., de Moya, M., Vosburgh, K.	J Trauma 63(2):285-8, discussion 288-90	Abdomainal Insufflation for Control of Bleeding After Severe Splenic Injury	2007

Trauma & Casualty Care at the Forum and Past Events
EVENT	DATE	SPEAKERS	DETAIL
Forum: Post-Traumatic Stress Disorder: Diagnosis & Therapy	Apr. 1, 2008	Ross Zafonte, DO: Spaulding Rehab Hospital; MGH Roger Pitman, MD: MGH	Traumatic Brain Injury Clinical Trials from the Past for the Future Neurological Soft Signs in Post-Traumatic Stress Disorder
Forum: Researchers Focus on Shock and Recovery	Oct. 16, 2007	Carl Hauser, MD, FACE, FCCM; BIDMC, HMS Alfred Ayala, PhD; Rhode Island Hospital, Brown University Wolfgang Junger, PhD; BIDMC, HMS	Post-Resuscitation Injury - Translational Approaches to Cell Signaling in Shock and Resusciation • Neutrophil Calcium Signaling in Shock and Trauma • The Role of Systemic Immune Cell Signaling in Whole Body Ischemia/Reperfusion Injury • Autocrine Regulation of Immune Cell Function • Translational Application of Cell Signaling Biology to the Care of Sick Patients
CIMIT Summer Education Series 2007	Jul. 10, 2007	Christopher Moore, PhD; MIT Leigh Hochberg, MD, PhD; Brown University, VA, HMS, MGH	Neurotechnology: Translating Basic Discoveries into Clinical Promise • Deciphering Cortical Electrophysiological Signals and their Applications for Brain-Body Interfaces
Forum: Doctors Discuss Challenges of Traumatic Brain Injury	May 22, 2007	Lee Schwamm, MD; MGH, HMS, MIT Marc de Moya, MD; MGH, HMS Mel Glenn, MD; Spaulding	• Acute and Chronic Consequences of Traumatic Brain Injury • A New Model of Severe Traumatic Brain Injury
Forum: Researchers Discuss Advances in Battlefield Medicine	May 8, 2007	Col. Geoffrey Ling, MD, PhD; DARPA, Walter Reed, Johns Hopkins Michael Callahan, MD, BTN & H, MSPH; DARPA	• Trauma Care and Soldier Performance
Forum: Experts Discuss Mass Casualty Incident Response	Apr. 24, 2007	Sandy Bogucki, MD, PhD; Yale, US Dept. of Health & Human Services Sheri Markwardt Harvey Mudd	• Decoding Cortical Electrophysiology for the Detection of Seizures

Program News
ARTICLE TITLE	PUBLICATION	DATE
Drug could turn soldiers into super-survivors	NewScientist	Jan. 27, 2010
Military rethinking 'golden hour' for injuries	USAToday.com	Aug. 25, 2009
Dr. Alam Elected as Mass. Chair of the American College of Surgeons Committee on Trauma	Press Release	Feb. 24, 2009
Made-for-the-military Products Put Brakes on Bleeding	CNN.com	March 2, 2007
More in Massachusetts Get Drug for Stroke	Boston Globe	October 20, 2006

Video: CIMIT Life-Saving Innovation in Early Stage of Trauma.

Program Leader

George Velmahos,
MD, PhD
gvelmahos@partners.org

CIMIT RESPONSIBILITIES
Program Leader,
Trauma & Casualty Care

CIMIT Community